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Independent Research Projects

Recent research in blood cancers, treatments, and associated diseases

Current Strategies to Improve Chimeric Antigen Receptor T (CAR-T) Cell Persistence (Peer Reviewed)

Chimeric antigen receptor T (CAR-T) cell therapy has transformed the field of immunology by redirecting T lymphocytes toward tumor antigens. Despite successes in attaining high remission rates as high as 90%, the performance of CAR therapy is limited by the survival of T cells. T cell persistence is crucial as it sustains immune response against malignancies, playing a critical role in cancer treatment outcomes.

2024-07-30 17_08_32-Cureus _ Current Strategies to Improve Chimeric Antigen Receptor T (CA

Strategies to Increase CAR-T Cell Persistence (Preprint)

ChemRxiv - Current strategies to improve CAR-T cell persistence

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Exploring CAR-T Cell Therapy

CAR-T cell therapy is a leading immunotherapy treatment primarily used to treat blood cancers. Recent studies have focused on enhancing CAR therapy by improving T-cell persistence. Learn more about this here. 

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Cellular Treatments for Graft-versus-Host disease

After an allogeneic stem cell transplant, many patients suffer from an associated disease called graft-versus-Host disease. Patients with blood cancer face a serious risk from this disease, and its important that we develop new therapies to treat it. 

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